JNCI is 75 Years Old!

Aminoglycosides use in patients over 75 years old.

OBJECTIVE to describe aminoglycoside use and nephrotoxicity in patients older than 75 years. DESIGN retrospective multicenter study. SETTING hospital department, rehabilitation, long-term care center. POPULATION patients ≥75 years old treated by aminoglycosides. RESULTS 184 patients, mean age: 84.4 years (range: 75-101). One hundred and twenty-seven patients received other nephrotoxic d...

Dermatology 75 years ago.

Part of the Dermatology Commons This Article is brought to you for free and open access by the Jefferson Digital Commons. The Jefferson Digital Commons is a service of Thomas Jefferson University's Center for Teaching and Learning (CTL). The Commons is a showcase for Jefferson books and journals, peer-reviewed scholarly publications, unique historical collections from the University archives, a...

The weaker sex is heterogametic: 75 years of Haldane's rule.

Celebrating 75 years of oestradiol.

Oestrogens exert important effects on the reproductive as well as many other organ systems in both men and women. The history of the discovery of oestrogens, the mechanisms of their synthesis, and their therapeutic applications are very important components of the fabric of endocrinology. These aspects provide the rationale for highlighting several key components of this story. Two investigator...

Decompression Only Versus Fusion Surgery for Lumbar Stenosis in Elderly Patients over 75 Years Old: Which is Reasonable?

As the population ages, more elderly patients suffer from spinal stenosis requiring lumbar fusion. However, there are few and conflicting results regarding the clinical outcome of lumbar fusion. The purpose of this study is to evaluate the safety and efficiency of posterior lumbar interbody fusion (PLIF) in over 75-year-old patients and analyze the relative effectiveness of lumbar spinal fusion...